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Apheris Co-Folding Application

Predict the 3D structure of macromolecule complexes with an emphasis on protein–ligand, protein–protein, and antibody–antigen interfaces using OpenFold3 and Boltz-2.

Use new co-folding models locally to comply with internal security policies and ensure that no data ever leaves your corporate network

Data preparation support with built-in quality control


Benchmarking and model inference capabilities


Seamless integration into enterprise research stacks

Optimized for enterprise security and scalability requirements for high-throughput sequence to structure modelling.

Designed for scientists, the Apheris Co-Folding Application is built to supplement rather than replace existing internal pipelines. It runs entirely in local or private cloud environments and integrates with enterprise R&D stacks.

Documentation

Local deployment

Ensure full data control, security, and compliance through local deployment. Keep your sensitive data away from unrestricted public co-folding servers where you don’t control how your data is protected.

Data preparation

Streamline data preparation using built-in quality control and preprocessing tools for faster onboarding

Model inference

Run model inference with input validation and batch execution – either programmatically via API or manually through a user-friendly GUI.

Benchmarking

Evaluate model performance with detailed accuracy metrics, confidence scores, and 3D visualizations.

Enterprise integration & scaleability

Handle high-demand workloads across many users and models over multiple GPUs – compatible with any cloud provider and cost-efficient through on-demand GPU provisioning.

Try the Apheris Co-Folding Application and start using structure-based models like OpenFold3 and Boltz-2 securely on your proprietary data.

Join the waitlist, and we’ll let you know as soon as it’s live.