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ApherisFold

Enables organizations to securely run the latest co-folding models, such as OpenFold3 and Boltz-2, directly within their own environments.

No data ever leaves your corporate network

Benchmark models on your in-house data


Explore outputs via a GUI or integrate them into existing workflows


Securely customize models to your domain of interests (on own or third-party data)

Optimized for enterprise security and scalability requirements

Designed for scientists ApherisFold is built to supplement rather than replace existing internal pipelines. It scales to many users, models and requests over multiple GPUs, and integrates into enterprise R&D stacks.

Documentation

Secure local inference

ApherisFold can be deployed locally such that no data leaves the corporate network and internal security policies are met.

In-house model benchmarking

Securely evaluate and compare models on your in-house data using performance guidelines and a benchmarking kit.

Model customization

Securely customize models to your domain of interests, either on your own data or on third-party data via federated data networks.

Visualization and integration

Explore 3D molecular visualization through a scientist-friendly GUI or connect outputs to existing drug discovery workflows programmatically via an API.

Dr. Lukas Pluska

Read Lukas' Co-Folding blog

to find out why co-folding models, such as AlphaFold 3, Boltz‑2, and OpenFold3, show decreased accuracy on novel targets. Learn how to critically assess their applicability domain, and why customizing these models to your own research tasks is essential for achieving meaningful results.

Co-Folding Blog

Securely use the latest co-folding models, like OpenFold3 and Boltz-2, on your proprietary data.

Join the waitlist, and we’ll let you know as soon as it’s live.